The hippocampus

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The hippocampus

Figure 1. Coronal slice through the transverse axis of the hippocampus. The black lines trace the classic ‘trisynaptic loop’. The red lines depict other important pathways in the hippocampus, including the direct projections from entorhinal cortex (EC) to all three CA fi elds, the feedback to the EC via the subiculum, the recurrent collateral circuitry of CA3, and the feedback projection from C...

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Hippocampus: Remembering the Choices

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Re-engineering the Hippocampus

As adult-generated neurons integrate into hippocampal circuits, they compete with mature neurons for inputs from the entorhinal cortex. By reducing spines on mature granule cells, McAvoy et al. (2016) find that new neurons integrate more efficiently, and this facilitates learning.

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Overworking the hippocampus

The postulated hippocampal comparator, like any other subsystem, must rely on "syntactic" patterns in its "input," and hence could not have the extraordinary powers Gray supposes. It may playa more modest role, but it is not the place "where it all comes together" for consciousness. Gray mistakenly thinks I have rejected the sort of theoretical enterprise he is undertaking, because, according t...

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Hippocampus.

Damage to the hippocampus and related brain regions causes a profound amnesic syndrome, in which patients are unable to form new memories about their experiences and about facts about the world. A number of theories have been proposed to explain hippocampal function. The theories that are currently most influential propose that the hippocampus is the substrate of declarative or episodic memory ...

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ژورنال

عنوان ژورنال: Current Biology

سال: 2015

ISSN: 0960-9822

DOI: 10.1016/j.cub.2015.10.049